The classic method for monitoring HCP impurities in biological products is ELISA, a method that obtains anti-HCP antibodies from animal immunizations, a key component of the assay, and it is critical to ensure that the antibodies used for ELISA cover as much of the HCP in the product as possible. Creative Diagnostics provides HCP coverage assay service that enables the detection and quantification of very low levels of HCP using a combination of immunoaffinity chromatography (IAC) and 2D DIGE analysis, which provides a comprehensive, detailed and efficient determination of ELISA HCP antibody coverage. https://qbd.creative-diagnosti....cs.com/services/iac-
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